Jackie fakes an MRI to get a phony prescription; Coop is distraught over the end of the campaign; Eddie returns.

Although struggling financially, Jackie and Kevin refuse an offer of help from O’Hara; Jackie discovers the friendship between Kevin and Eddie.

Kevin invites Jackie to a midnight rendezvous in order to give her a new wedding ring; the comatose movie critic wakes up but his tastes have radically changed. Eddie learns the truth about Jackie’s family. O’Hara’s ailing mother is admitted. Jackie attempts to commit suicide but fails. This episode ends the first season for Nurse [...]

Eddie is replaced by an automatic pill dispensing machine. Zoey administers the wrong dose of a painkiller to a movie critic, who lapses into a coma.

Jackie makes an unusual ploy to get Coop off her back about the fake organ donor card. O’Hara helps Jackie remove her wedding ring before a quickie with Eddie. Jackie begins mother-daughter dance lessons with Grace.

Jackie admits a dying patient she has treated before, learns that O’Hara has betrayed her secrets to a sister in Paris, suffers a drug-induced nosebleed, and forges an organ donation form in Coop’s name. the parents of the baby that Akalitus is raising come forward to reclaim their child.

Jackie discovers that a new temp nurse is abusing drugs, but when she confronts him, he calls her on hypocrisy. Mrs. Akalitus still has the foundling infant left at the hospital. Coop reveals to Eddie that Jackie has a child.

A man is admitted to the ER with a steak knife in his chest, after an attack by the ex-husband of a woman he was dating for the first time. Mrs. Akalitus takes charge of a foundling abandoned at the nurses’ station. O’Hara has a personal crisis.

A fellow nurse and old friend of Jackie’s checks into the hospital with terminal lung cancer, and asks Jackie to help end her life; Dr. Cooper’s mother is admitted with a gall bladder attack and reveals a family secret about her son’s upbringing.

It’s a topsy-turvy night shift for the All-Saints staff. Jackie bucks the system to assist a 10-year-old girl caring for her lupus-stricken mother, while male bonding between Eddie and Dr. Cooper puts a damper on Jackie’s usual mid-shift tryst in the pharmacy back-room. Mo-Mo spends the night simultaneously deflecting Thor’s advances and enjoying the fringe [...]

Jackie and Kevin are rattled by concerns raised at a school meeting regarding Grace’s psychological development. Zoey, lamenting a day of “unexciting” cases being assigned to her, ends up dealing with a key, tragic “first” every nurse must overcome. Meanwhile, Dr. O’Hara, in Jackie’s absence, humorously struggles with the gushing, innocent gratitude of her young [...]

Kevin shares his concern regarding Grace’s mounting anxiety with Jackie. At work, Jackie must deal with a dying man (Eli Wallach) who refuses further treatment, while Eddie faces the possibility of being replaced by an automated dispensory. Meanwhile, Zoey must work up the courage to ask for her new stethoscope back after Dr. O’Hara takes [...]

With Sweet ‘n All packets full of ground-up Percocet to get her through the day, Jackie shifts blame for the resurfaced flushed ear on rookie Zoey, and must swallow her pride and tell Coop that he had been right about diagnosing a patient’s unlikely aneurysm.

Veteran emergency room nurse Jackie Peyton navigates the traffic of Manhattan’s All-Saints Hospital, embracing a subtle drug addiction and making tough and sometimes unethical and even illegal decisions for the “good” of her patients. Clashing with cocky young surgeon Dr. Fitch “Coop” Cooper and begrudgingly training naïve and perky new Nurse Zoey, Jackie maintains an [...]